Polio Situation at the end of 2022

Sunday, January 29, 2023

As 2022 draws to a close, I wanted to thank  each and every  one of you for the incredible work and contributions you have made to the global effort to eradicate polio once and for all.  You are all far too many to name individually, so I would ask  you  to  share this note with  all of  your own respective networks to pass on my gratitude.

 

2022, I believe, will go down  as  a   year of ‘contrasts’, in the global effort to eradicate polio.  On the one hand, we saw polio re-emerge in places such as New York and London, in south-east Africa, and an increase in new cases in Pakistan.  But on the other hand, 2022 saw perhaps some  of the most significant and important progress that we have ever seen  and this is setting up the global effort for a unique opportunity for success in 2023. 

 

While detection of polio from anywhere that it had previously been gone is of course a  setback , the reality is that events such as New York and London, and indeed elsewhere, are being appropriately managed.   We must focus our eye clearly on those areas which hold the key to a polio-free world, namely in the  endemics and  consequential geographies.  And here the news is  actually really  encouraging.

 

In Pakistan, notwithstanding  the increase in new cases, the outbreak is  geographically confined, thanks to concerted emergency efforts led by the government and supported by partners.  All cases are concentrated in just six districts of one province, out of a total of 180 districts in the country.  And while virus has been detected outside of these areas it  has not succeeded in re-establishing a  foothold  outside the core endemic zone. I n 2020, the country was affected by 11 separate and individual chains of transmission .  This was reduced to four in 2021, and in 2022, only a single chain remains.  It means individual virus lines are being successfully knocked out.  It means the approaches being implemented in the country are working.

 

In Afghanistan too, an epidemiological  deep-dive  reveals an encouraging  picture.  Just over twelve months on from the political and security transition in country, access to all children continues to improve, including more than 3.5 million children who had not been reached for almost five years,  albeit against a tragic backdrop of a severe and acute humanitarian crisis.   Out of the country’s 34 provinces, just two remain active with endemic transmission.  And  where Afghanistan was once  affected by eight separate transmission chains, in 2022 there now remains   just two.  

 

Such epidemiological and virological  progress is similar to  what epidemiologists observed during the ‘end game’ efforts in other previous global polio  reservoirs, notably Nigeria,  India  and Egypt, all giving hope that these remaining two endemic countries are on the right track.

 

In terms of  cVDPV  outbreaks, almost  90 percent of the disease burden is in three sub-national geographic areas, namely eastern  DR Congo, northern  Yemen  and northern Nigeria .  These areas also overlap with some of the highest proportion of ‘zero dose’ children,  ie  those children who are either un- or under-vaccinated.  The situation in northern Nigeria is particularly  encouraging:   having seeded outbreaks in more than 19 countries, Nigeria accounted for two-thirds of all global cases in 2021.  In the second half of 2022, however, we have seen a dramatic decrease in new cases, with only nine reported during that time.  And although the outbreaks in Yemen and  DR Congo  continue to expand, there is a clear plan for early 2023 to urgently address these respective situations.   T he new nOPV2 ,  a key tool in this fight,  continues to be rolled-out at an accelerated pace, with more than 530 million doses now administered.  

 

This brings us of course to the WPV outbreak in south-east Africa.  Following detection of the outbreak in February, a series of multi-country outbreak response campaigns were immediately launched, in five countries of the subregion, to urgently stop this outbreak.  This effort is ongoing, and quality of outbreak response continues to improve from campaign to campaign.  And as the case in the other ‘most consequential geographies’, the focus is entirely on reaching zero-dose children, by concentrating technical capacity and support on those areas with the highest proportion of underreached children and communities.  No WPV1 detection have been recorded outside a single province in northern Mozambique in 2022.  We are not yet at the end but momentum continues to be sustained  and this is extremely encouraging.

 

2022 was of course the first year of the new GPEI Strategy - Delivering on a Promise and this very much takes the COVID-19 reality into account.  In addition to adapting our polio operations, cross-programmatic integration has been accelerated by the COVID-19 pandemic.  Polio staff across the world continue to contribute to the COVID-19 response and immunization recovery efforts, together with the introduction and administration of COVID-19 vaccines, as highlighted in this  report.  This provides clear evidence of the broader value of the polio network and its work to align its priorities with broader public health efforts, notably global vaccine and immunization strategies.  It also speaks to the importance of effectively  transitioning this infrastructure , to ensure that it will continue to benefit broader public health, emergencies and pandemic response efforts, long after the disease is gone. 

 

As 2022 draws to a close, the  programme  is on  a   strong epidemiological,  operational  and virological footing.  We are absolutely on the right track, and this realization should motivate all partners and stakeholders into overdrive.  Throughout 2022, we saw tremendous displays of  global support , ranging from the World Health Assembly, to the Rotary International Convention in Houston, USA, to the G7 and G20.  Perhaps the most significant signal of support came at the global  GPEI Pledging Moment  at the World Health Summit in October 2022, in Berlin, Germany, co-hosted by the Government of Germany, where global leaders pledged an incredible US$2.6 billion to the effort.  As 2022 draws to a close, we have also received very positive signals of support from the UK and the EU/EIB. 

 

Challenges remain ahead.  Zero-dose children  have to  be reached in the most consequential geographies.  Remaining financial resources to achieve success  have to  be mobilized.  But  in spite of  initial appearances, 2022 put the world on a  strong footing for success in 2023.  And of course, that is the target clearly listed in the GPEI Strategy 2022-2026:  to interrupt all remaining virus transmission by end-2023 and to achieve global certification by no later than end-2026.   

 

 

There is a clear momentum as the year draws to a close, that must be carried into 2023 for a final concerted push.  Success is in our hands.  And all of you have brought us here:  thanks to your individual efforts, you have brought the world on the threshold of being polio-free.  Your efforts have saved children from lifelong paralysis, have saved lives.  On behalf of the GPEI, all I can say is:  Thank you for all you have done for polio eradication!  If we all redouble our efforts one final time, I am sure we will make it in 2023.

 

Allow me to finish with a quote by our fellow polio eradicator, friend and GPEI vaccinator  Sadiya from Kano , Nigeria, who addressed the Pledging Event in Berlin by video.  She told the gathering: “ Together , we can end polio in the world.  I will try my best.  I hope you will too.”   Let us follow  Sadiya’s  example, let us do our best as well.   Together , let us end polio.

 

I wish all of you and your close ones a very happy, peaceful,  healthy  and blessed festive season, and all the very best wishes for a successful 2023.

 

Best regards

 

Aidan O’Leary

Aidan O'Leary, Director Polio at WHO on the polio situation at the end of 2022